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Gajewski, Thomas F.
One or more keywords matched the following items that are connected to Gajewski, Thomas F.
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Concept Adjuvants, Immunologic
Concept Angiotensin II
Concept Antibodies, Neoplasm
Concept Antibodies, Viral
Concept Antigen-Presenting Cells
Concept Aged, 80 and over
Concept Adolescent
Concept Aged
Concept Blood Pressure
Concept Amino Acid Sequence
Concept Administration, Oral
Concept Adult
Concept Antibodies, Anti-Idiotypic
Concept Antibodies, Monoclonal
Concept Cyclosporins
Concept B-Lymphocytes
Concept Base Sequence
Concept Benzamides
Concept Benzazepines
Concept Benzimidazoles
Concept Biological Availability
Concept Carmustine
Concept Awards and Prizes
Concept DNA Damage
Concept Autoantibodies
Concept Carbon Monoxide
Concept Child
Concept Foreign Bodies
Concept Ciprofloxacin
Concept Classification
Concept Concanavalin A
Concept Colony-Stimulating Factors
Concept DNA-Binding Proteins
Concept Cycloheximide
Concept Drug Synergism
Concept Dendritic Cells
Concept Diet
Concept Immunosuppressive Agents
Concept Interleukin-2
Concept Interleukins
Concept DNA Repair
Concept Cause of Death
Concept DNA, Neoplasm
Concept Glucocorticoids
Concept Growth Inhibitors
Concept Immunologic Factors
Concept Mammary Neoplasms, Experimental
Concept Congresses as Topic
Concept DNA
Concept Melanoma, Experimental
Concept Indoles
Concept Interferons
Concept Mice, Inbred C3H
Concept Muscle, Smooth
Concept Mycoplasma Infections
Concept Killer Cells, Natural
Concept Guanosine Triphosphate
Concept Oncogenes
Concept Government Agencies
Concept T-Lymphocytes, Helper-Inducer
Concept Dose-Response Relationship, Drug
Concept Immune Sera
Concept Liver Neoplasms
Concept Patient Care Planning
Concept Enzyme-Linked Immunosorbent Assay
Concept Flow Cytometry
Concept Fluorescent Antibody Technique
Concept Infant
Concept Interleukin-1
Concept International Cooperation
Concept Multigene Family
Concept Leukocytes, Mononuclear
Concept Medicare
Concept Lymphocyte Depletion
Concept Lymphoproliferative Disorders
Concept Macrophages
Concept Mandible
Concept Peptidyl-Dipeptidase A
Concept Leukocytes
Concept Mice, Inbred A
Concept Mice, Inbred Strains
Concept Pilot Projects
Concept Lymphopenia
Concept Needles
Concept Mice, Inbred CBA
Concept Mice, Transgenic
Concept Neoplasm Transplantation
Concept Pneumonia, Viral
Concept Pregnancy
Concept Immunoglobulin Variable Region
Concept Immunohistochemistry
Concept Opportunistic Infections
Concept Organoplatinum Compounds
Concept Molecular Sequence Data
Concept Neoplastic Cells, Circulating
Concept Osteoma, Osteoid
Concept Oximes
Concept Pancreatic Neoplasms
Concept Mesothelioma
Concept Mice, Inbred BALB C
Concept Mice, Inbred C57BL
Concept Mice, Nude
Concept Middle Aged
Concept Cricetinae
Concept Hot Temperature
Concept Peptide Fragments
Concept Interleukin-3
Concept Wilms Tumor
Concept Neurilemmoma
Concept Leukemia L1210
Concept Peritoneal Cavity
Concept Nucleotidyltransferases
Concept Ovalbumin
Concept Lipopolysaccharides
Concept Liver
Concept Luciferases
Concept Lymphokines
Concept Major Histocompatibility Complex
Concept Oligopeptides
Concept Oocytes
Concept Osteochondritis
Concept Osteoma
Concept Parietal Lobe
Concept Phosphorylation
Concept Morpholines
Concept Pleura
Concept Oxygen
Concept Polymers
Concept Prostatic Neoplasms
Concept Thymoma
Concept Protein-Tyrosine Kinases
Concept Protein Processing, Post-Translational
Concept Proto-Oncogene Proteins
Concept Forecasting
Concept Hodgkin Disease
Concept Guanine
Concept Respiratory Muscles
Concept Risk Factors
Concept Protein Kinases
Concept Receptors, Antigen, B-Cell
Concept Interferon-gamma
Concept Intestinal Mucosa
Concept Reagent Kits, Diagnostic
Concept Regulatory Sequences, Nucleic Acid
Concept Sarcoma, Experimental
Concept Interleukin-6
Concept Societies, Medical
Concept Surgical Procedures, Operative
Concept Humans
Concept Immunization
Concept Tomography, X-Ray Computed
Concept Protein Biosynthesis
Concept Sunlight
Concept Specific Pathogen-Free Organisms
Concept Informed Consent
Concept Interferon Type I
Concept Thymus Neoplasms
Concept Tumor Necrosis Factor-alpha
Concept Xenopus laevis
Concept Drug Design
Concept Protein Engineering
Concept Ketoconazole
Concept Vaccination
Concept Octreotide
Concept Lymphoid Tissue
Concept Lymphoma, Follicular
Concept Hematopoietic Stem Cell Transplantation
Concept Th1 Cells
Concept Risk Assessment
Concept Drug Resistance, Neoplasm
Concept Antibodies, Blocking
Concept Radiopharmaceuticals
Concept Reverse Transcriptase Polymerase Chain Reaction
Concept Caspases
Concept Guanine Nucleotide Exchange Factors
Concept Mitogen-Activated Protein Kinases
Concept Transforming Growth Factor beta
Concept NF-kappa B
Concept Osteonectin
Concept Up-Regulation
Concept 8-Bromo Cyclic Adenosine Monophosphate
Concept Quinolones
Concept Mice, Inbred DBA
Concept Muromonab-CD3
Concept Radiosurgery
Concept Lymph Nodes
Concept Lymphatic Metastasis
Concept Mitochondria
Concept CD4-Positive T-Lymphocytes
Concept Interleukin-4
Concept Lymphocytes, Tumor-Infiltrating
Concept Cytochalasin D
Concept Drug Approval
Concept Lymphocyte Function-Associated Antigen-1
Concept T-Lymphocyte Subsets
Concept Immunotherapy, Active
Concept Medical Oncology
Concept Melanoma
Concept Methionine
Concept Minocycline
Concept Treatment Outcome
Concept Neoplasm Metastasis
Concept Neoplasm Recurrence, Local
Concept Neoplasms, Experimental
Concept Point Mutation
Concept Interferon-alpha
Concept Mice, Knockout
Concept CD8-Positive T-Lymphocytes
Concept Chemokines
Concept Disease Progression
Concept Transplantation Conditioning
Concept Muscle, Skeletal
Concept ras Proteins
Concept Interleukin-12
Concept Apoptosis Regulatory Proteins
Concept Th2 Cells
Concept Receptors, CCR5
Concept L-Selectin
Concept src-Family Kinases
Concept Angiogenesis Inhibitors
Concept Kv1.3 Potassium Channel
Concept Fas Ligand Protein
Concept Gene Regulatory Networks
Concept ras Guanine Nucleotide Exchange Factors
Concept MAP Kinase Kinase Kinases
Concept Chemokines, CC
Concept Diacylglycerol Kinase
Concept Potassium Channel Blockers
Concept Interleukin-23
Concept Chemokine CXCL9
Concept Lymphocyte Count
Concept Immunoconjugates
Concept Protein Tyrosine Phosphatases
Concept Parietal Bone
Concept Nucleotides, Cyclic
Concept Receptors, Purinergic P2X7
Concept Oncogene Proteins, Viral
Concept Intercellular Signaling Peptides and Proteins
Concept Vascular Endothelial Growth Factor Receptor-2
Concept Consensus
Concept Internationality
Concept MAP Kinase Kinase 4
Concept Positron-Emission Tomography
Concept Systems Biology
Concept Papillomavirus E7 Proteins
Concept Chromatin Immunoprecipitation
Concept Mitogen-Activated Protein Kinase 3
Concept Biological Specimen Banks
Concept Proto-Oncogene Proteins c-bcl-2
Concept Cyclin-Dependent Kinase Inhibitor p16
Concept Proto-Oncogene Proteins B-raf
Concept Indoleamine-Pyrrole 2,3,-Dioxygenase
Concept Caspase 1
Concept Proto-Oncogene Proteins c-kit
Concept Internet
Concept Oligonucleotide Array Sequence Analysis
Concept Access to Information
Concept Evidence-Based Medicine
Concept Papillomaviridae
Concept Biotinylation
Concept Interferon Regulatory Factor-3
Concept bcl-X Protein
Concept Type C Phospholipases
Concept Promoter Regions, Genetic
Concept Mice
Concept Protein Kinase C
Concept Psoriasis
Concept Quinazolines
Concept Tumor Necrosis Factor Ligand Superfamily Member 14
Concept National Cancer Institute (U.S.)
Concept RNA, Ribosomal, 16S
Concept Scorpion Venoms
Concept Interleukin-23 Subunit p19
Concept Glycogen Synthase Kinase 3
Concept Vascular Endothelial Growth Factor Receptor-3
Concept Sulfonamides
Concept Biomedical Research
Concept Glutamate Carboxypeptidase II
Concept Xanthones
Concept Proto-Oncogene Proteins c-cbl
Concept Rats
Concept SOX9 Transcription Factor
Concept Benzodioxoles
Concept TOR Serine-Threonine Kinases
Concept Real-Time Polymerase Chain Reaction
Concept Antibodies, Monoclonal, Humanized
Concept Immunoprecipitation
Concept Sex Factors
Concept Spinal Cord Neoplasms
Concept Spleen
Concept Adaptor Proteins, Signal Transducing
Concept Chemokine CXCL10
Concept Chemokine CCL19
Concept T-Lymphocytes, Cytotoxic
Concept Temperature
Concept Immunoblotting
Concept Blotting, Western
Concept Down-Regulation
Concept NFATC Transcription Factors
Concept PTEN Phosphohydrolase
Concept MutS Homolog 2 Protein
Concept Integrin alphaXbeta2
Concept Receptors, Lymphocyte Homing
Concept Lymphoma, B-Cell
Concept CD4-CD8 Ratio
Concept Cyclosporine
Concept Tryptophan Oxygenase
Concept Blotting, Northern
Concept Polymyositis
Concept Survival Rate
Concept Coronavirus Infections
Concept Skin Transplantation
Concept Lymphocyte Subsets
Concept Polymerase Chain Reaction
Concept Proto-Oncogene Proteins p21(ras)
Concept Patient Selection
Concept Organ Transplantation
Concept Interferon-beta
Concept Protein Prenylation
Concept Receptors, Death Domain
Concept Myeloid Differentiation Factor 88
Concept Leukocyte Common Antigens
Concept Receptors, CXCR3
Concept Receptors, CCR2
Concept Chemokine CCL21
Concept Receptors, Chemokine
Concept Mitogen-Activated Protein Kinase 1
Concept Calcium-Calmodulin-Dependent Protein Kinases
Concept Xenograft Model Antitumor Assays
Concept Cell Lineage
Concept Peptide Library
Concept Gadolinium DTPA
Concept O(6)-Methylguanine-DNA Methyltransferase
Concept JNK Mitogen-Activated Protein Kinases
Concept Extracellular Signal-Regulated MAP Kinases
Concept T-Lymphocytes, Regulatory
Concept STAT1 Transcription Factor
Concept STAT5 Transcription Factor
Concept Lymphohistiocytosis, Hemophagocytic
Concept GRB2 Adaptor Protein
Concept I-kappa B Kinase
Concept gp100 Melanoma Antigen
Concept TNF-Related Apoptosis-Inducing Ligand
Concept Granzymes
Concept Genome-Wide Association Study
Concept Citrus paradisi
Concept RNA, Small Interfering
Concept Antibodies, Monoclonal, Murine-Derived
Concept Pandemics
Concept Ribosomal Protein S6 Kinases, 70-kDa
Concept Vascular Endothelial Growth Factor A
Concept Oncolytic Virotherapy
Concept STAT6 Transcription Factor
Concept bcl-Associated Death Protein
Concept Proto-Oncogene Proteins c-fyn
Concept Receptor, Fibroblast Growth Factor, Type 3
Concept ZAP-70 Protein-Tyrosine Kinase
Concept Phospholipase C gamma
Concept Kaplan-Meier Estimate
Concept Amyloid Precursor Protein Secretases
Concept Receptors, CCR7
Concept MART-1 Antigen
Concept Antibodies
Concept Brain Neoplasms
Concept Chyle
Concept Growth Substances
Concept Immunoglobulins
Concept Intestinal Obstruction
Concept Lymphocytes
Concept Lymphoma, Non-Hodgkin
Concept Metacarpus
Concept Mice, Mutant Strains
Concept Mucous Membrane
Concept Neoplasm Invasiveness
Concept Neuroblastoma
Concept Peptides
Concept Phenotype
Concept Prospective Studies
Concept Proto-Oncogenes
Concept Respiration, Artificial
Concept Serine Endopeptidases
Concept T-Lymphocytes
Concept Thymus Gland
Concept Granulocyte-Macrophage Colony-Stimulating Factor
Concept Cytokines
Concept Macrophage-Activating Factors
Concept Microglia
Concept DNA Primers
Concept Neoplasm, Residual
Concept Macrolides
Concept fas Receptor
Concept Maximum Tolerated Dose
Concept Myeloid Cells
Concept Protein Array Analysis
Concept Proto-Oncogene Proteins c-akt
Concept CARD Signaling Adaptor Proteins
Concept p21-Activated Kinases
Concept Young Adult
Concept Patient Safety
Academic Article B7-1 but not B7-2 efficiently costimulates CD8+ T lymphocytes in the P815 tumor system in vitro.
Academic Article Liver of MRL/lpr mice contain interleukin-4-producing lymphocytes and accessory cells that support the proliferation of Th2 helper T lymphocyte clones.
Academic Article Induction of a cytolytic T-cell response in mice with a recombinant adenovirus coding for tumor antigen P815A.
Academic Article Antigen-specific regression of established tumors induced by active immunization with irradiated IL-12- but not B7-1-transfected tumor cells.
Academic Article Apoptosis meets signal transduction: elimination of a BAD influence.
Academic Article The expression of mouse gene P1A in testis does not prevent safe induction of cytolytic T cells against a P1A-encoded tumor antigen.
Academic Article Blocked Ras activation in anergic CD4+ T cells.
Academic Article The immune system as anti-tumor sentinel: molecular requirements for an anti-tumor immune response.
Academic Article Interleukin-12-secreting human papillomavirus type 16-transformed cells provide a potent cancer vaccine that generates E7-directed immunity.
Academic Article B7-1 engagement of cytotoxic T lymphocyte antigen 4 inhibits T cell activation in the absence of CD28.
Academic Article Cutting edge: differentiation of antitumor CTL in vivo requires host expression of Stat1.
Academic Article Polymyositis with respiratory muscle weakness requiring mechanical ventilation in a patient with metastatic thymoma treated with octreotide.
Academic Article Antigen-specific blockade of T cells in vivo using dimeric MHC peptide.
Academic Article CD28 is not required for c-Jun N-terminal kinase activation in T cells.
Academic Article Improved efficacy of dendritic cell vaccines and successful immunization with tumor antigen peptide-pulsed peripheral blood mononuclear cells by coadministration of recombinant murine interleukin-12.
Academic Article Allogeneic stem-cell transplantation of renal cell cancer after nonmyeloablative chemotherapy: feasibility, engraftment, and clinical results.
Academic Article Cutting edge: spontaneous rejection of poorly immunogenic P1.HTR tumors by Stat6-deficient mice.
Academic Article Immunization with Melan-A peptide-pulsed peripheral blood mononuclear cells plus recombinant human interleukin-12 induces clinical activity and T-cell responses in advanced melanoma.
Academic Article T cell development and function in CrkL-deficient mice.
Academic Article Death of peripheral CD8+ T cells in the absence of MHC class I is Fas-dependent and not blocked by Bcl-xL.
Academic Article Absence of CTLA-4 lowers the activation threshold of primed CD8+ TCR-transgenic T cells: lack of correlation with Src homology domain 2-containing protein tyrosine phosphatase.
Academic Article Epitope spreading upon P815 tumor rejection triggered by vaccination with the single class I MHC-restricted peptide P1A.
Academic Article Temozolomide for melanoma: new toxicities and new opportunities.
Academic Article Differential Ras signaling via the antigen receptor and IL-2 receptor in primary T lymphocytes.
Academic Article Cutting edge: targeted ligation of CTLA-4 in vivo by membrane-bound anti-CTLA-4 antibody prevents rejection of allogeneic cells.
Academic Article Actin cytoskeleton regulates calcium dynamics and NFAT nuclear duration.
Academic Article Depletion of normal B cells with rituximab as an adjunct to IL-2 therapy for renal cell carcinoma and melanoma.
Academic Article Long-term follow-up of nonmyeloablative allogeneic stem cell transplantation for renal cell carcinoma: The University of Chicago Experience.
Academic Article Gene array and protein expression profiles suggest post-transcriptional regulation during CD8+ T cell differentiation.
Academic Article Murine Th1 and Th2 clones proliferate optimally in response to distinct antigen-presenting cell populations.
Academic Article Disparate functions of immature and mature human myeloid dendritic cells: implications for dendritic cell-based vaccines.
Academic Article Absence of programmed death receptor 1 alters thymic development and enhances generation of CD4/CD8 double-negative TCR-transgenic T cells.
Academic Article Update on vaccines for solid tumors.
Academic Article On the TRAIL toward death receptor-based cancer therapeutics.
Academic Article Cutting edge: cytotoxic granule polarization and cytolysis can occur without central supramolecular activation cluster formation in CD8+ effector T cells.
Academic Article Homeostatic proliferation as an isolated variable reverses CD8+ T cell anergy and promotes tumor rejection.
Academic Article Phase II trial of the O6-alkylguanine DNA alkyltransferase inhibitor O6-benzylguanine and 1,3-bis(2-chloroethyl)-1-nitrosourea in advanced melanoma.
Academic Article Tumor progression despite massive influx of activated CD8(+) T cells in a patient with malignant melanoma ascites.
Academic Article Phase II study of the Flk-1 tyrosine kinase inhibitor SU5416 in advanced melanoma.
Academic Article Homeostatic proliferation plus regulatory T-cell depletion promotes potent rejection of B16 melanoma.
Academic Article Phase I/II trial of tremelimumab in patients with metastatic melanoma.
Academic Article Failure at the effector phase: immune barriers at the level of the melanoma tumor microenvironment.
Academic Article The HLA-A2-restricted PSMA peptide LLHETDSAV is poorly immunogenic in patients with metastatic prostate cancer.
Academic Article Chemokine expression in melanoma metastases associated with CD8+ T-cell recruitment.
Academic Article Protein kinase Ctheta focusing at the cSMAC is a consequence rather than cause of TCR signaling and is dependent on the MEK/ERK pathway.
Academic Article Identifying and overcoming immune resistance mechanisms in the melanoma tumor microenvironment.
Academic Article Immune resistance orchestrated by the tumor microenvironment.
Academic Article A phase II study of oxaliplatin, docetaxel, and GM-CSF in patients with previously treated advanced melanoma.
Academic Article Phenotypic and functional analysis of murine CD3+,CD4-,CD8- TCR-gamma delta-expressing peripheral T cells.
Academic Article Efficacy and safety of ipilimumab monotherapy in patients with pretreated advanced melanoma: a multicenter single-arm phase II study.
Academic Article Improved melanoma survival at last! Ipilimumab and a paradigm shift for immunotherapy.
Academic Article Glucose deprivation inhibits multiple key gene expression events and effector functions in CD8+ T cells.
Academic Article Emerging strategies in regulatory T-cell immunotherapies.
Academic Article Molecular profiling of melanoma and the evolution of patient-specific therapy.
Academic Article Evidence implicating the Ras pathway in multiple CD28 costimulatory functions in CD4+ T cells.
Academic Article Innate immune sensing of cancer: clues from an identified role for type I IFNs.
Academic Article A designer ligand specific for Kv1.3 channels from a scorpion neurotoxin-based library.
Academic Article Future perspectives in melanoma research. Meeting report from the "Melanoma research: a bridge from Naples to the World. Napoli, December 5th-6th 2011".
Academic Article Glucose availability regulates IFN-gamma production and p70S6 kinase activation in CD8+ effector T cells.
Academic Article Evidence implicating I region-restricted antigen presentation in alloantigen and nominal antigen recognition by a dual-reactive helper T lymphocyte clone.
Academic Article Regulation of T-cell activation: differences among T-cell subsets.
Academic Article Harnessing the immune response.
Academic Article Transcriptional regulator early growth response gene 2 (Egr2) is required for T cell anergy in vitro and in vivo.
Academic Article Clinical development of mAbs to block the PD1 pathway as an immunotherapy for cancer.
Academic Article Induction of the increased Fyn kinase activity in anergic T helper type 1 clones requires calcium and protein synthesis and is sensitive to cyclosporin A.
Academic Article Differential requirement for protein tyrosine kinase Fyn in the functional activation of antigen-specific T lymphocyte clones through the TCR or Thy-1.
Academic Article An adenoviral vector encoding dominant negative Cbl lowers the threshold for T cell activation in post-thymic T cells.
Academic Article CARMA1 controls an early checkpoint in the thymic development of FoxP3+ regulatory T cells.
Academic Article SITC/iSBTc Cancer Immunotherapy Biomarkers Resource Document: online resources and useful tools - a compass in the land of biomarker discovery.
Academic Article Anti-proliferative effect of IFN-gamma in immune regulation. II. IFN-gamma inhibits the proliferation of murine bone marrow cells stimulated with IL-3, IL-4, or granulocyte-macrophage colony-stimulating factor.
Academic Article Control of T lymphocyte signal transduction through clonal anergy.
Academic Article Expression and function of CTLA-4 in Th1 and Th2 cells.
Academic Article Increasing tumor antigen expression overcomes "ignorance" to solid tumors via crosspresentation by bone marrow-derived stromal cells.
Academic Article PD-L1/B7H-1 inhibits the effector phase of tumor rejection by T cell receptor (TCR) transgenic CD8+ T cells.
Academic Article Dose-ranging pharmacodynamic study of tipifarnib (R115777) in patients with relapsed and refractory hematologic malignancies.
Academic Article Overcoming immune resistance in the tumor microenvironment by blockade of indoleamine 2,3-dioxygenase and programmed death ligand 1.
Academic Article Lymphoma-infiltrating immune cells.
Academic Article Phase II study of immunomodulation with granulocyte-macrophage colony-stimulating factor, interleukin-2, and rituximab following autologous stem cell transplant in patients with relapsed or refractory lymphomas.
Academic Article Molecular profiling to identify relevant immune resistance mechanisms in the tumor microenvironment.
Academic Article Review of the 25th annual scientific meeting of the International Society for Biological Therapy of Cancer.
Academic Article Ocular melanoma metastasis to the cervical spine.
Academic Article Cancer immunotherapy.
Academic Article [2- and multistage surgical procedures on the intestines].
Academic Article [Parotitis as a postoperative complication].
Academic Article [Perthes' syndrome after crushing of the thorax].
Academic Article [Osteoid osteoma].
Academic Article Future perspectives in melanoma research. Meeting report from the "Melanoma Bridge. Napoli, December 2nd-4th 2012".
Academic Article Cancer classification using the Immunoscore: a worldwide task force.
Academic Article Phase II study of the Src kinase inhibitor saracatinib (AZD0530) in metastatic melanoma.
Academic Article Type I interferon response and innate immune sensing of cancer.
Academic Article Cancer immunotherapy.
Academic Article Phase II study of the farnesyltransferase inhibitor R115777 in advanced melanoma (CALGB 500104).
Academic Article Egr2-dependent gene expression profiling and ChIP-Seq reveal novel biologic targets in T cell anergy.
Academic Article Cancer immunotherapy strategies based on overcoming barriers within the tumor microenvironment.
Academic Article Imatinib for melanomas harboring mutationally activated or amplified KIT arising on mucosal, acral, and chronically sun-damaged skin.
Academic Article Combination of vemurafenib and cobimetinib in patients with advanced BRAF(V600)-mutated melanoma: a phase 1b study.
Academic Article Future perspectives in melanoma research: meeting report from the "Melanoma Bridge", Napoli, December 5th-8th 2013.
Academic Article Therapeutic activity of high-dose intratumoral IFN-ß requires direct effect on the tumor vasculature.
Academic Article Metabolic response by FDG-PET to imatinib correlates with exon 11 KIT mutation and predicts outcome in patients with mucosal melanoma.
Academic Article Conditional deletion of PTEN in peripheral T cells augments TCR-mediated activation but does not abrogate CD28 dependency or prevent anergy induction.
Academic Article STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors.
Academic Article The Society for Immunotherapy of Cancer consensus statement on tumour immunotherapy for the treatment of cutaneous melanoma.
Academic Article Primary murine CD4+ T cells fail to acquire the ability to produce effector cytokines when active Ras is present during Th1/Th2 differentiation.
Academic Article STING-dependent cytosolic DNA sensing mediates innate immune recognition of immunogenic tumors.
Academic Article Innate and adaptive immune cells in the tumor microenvironment.
Academic Article A randomized pilot phase I study of modified carcinoembryonic antigen (CEA) peptide (CAP1-6D)/montanide/GM-CSF-vaccine in patients with pancreatic adenocarcinoma.
Academic Article Effect of selumetinib vs chemotherapy on progression-free survival in uveal melanoma: a randomized clinical trial.
Academic Article Phase II Study of Nilotinib in Melanoma Harboring KIT Alterations Following Progression to Prior KIT Inhibition.
Academic Article Non-redundant requirement for CXCR3 signalling during tumoricidal T-cell trafficking across tumour vascular checkpoints.
Academic Article The Next Hurdle in Cancer Immunotherapy: Overcoming the Non-T-Cell-Inflamed Tumor Microenvironment.
Academic Article Commensal Bifidobacterium promotes antitumor immunity and facilitates anti-PD-L1 efficacy.
Academic Article Future perspectives in melanoma research: meeting report from the "Melanoma Bridge": Napoli, December 3rd-6th 2014.
Academic Article A phase II study of cediranib, an oral VEGF inhibitor, in previously untreated patients with metastatic or recurrent malignant melanoma.
Academic Article Tumor and Host Factors Controlling Antitumor Immunity and Efficacy of Cancer Immunotherapy.
Academic Article Antagonism of the STING Pathway via Activation of the AIM2 Inflammasome by Intracellular DNA.
Academic Article MYC - a thorn in the side of cancer immunity.
Academic Article The composition of the microbiota modulates allograft rejection.
Academic Article The host STING pathway at the interface of cancer and immunity.
Academic Article Manipulating the microbiome to improve the efficacy of immunotherapy.
Academic Article NK Cells Restrain Spontaneous Antitumor CD8+ T Cell Priming through PD-1/PD-L1 Interactions with Dendritic Cells.
Academic Article Unlocking tumor vascular barriers with CXCR3: Implications for cancer immunotherapy.
Academic Article Relationship between physician-adjudicated adverse events and patient-reported health-related quality of life in a phase II clinical trial (NCT01143402) of patients with metastatic uveal melanoma.
Academic Article Stem cell-like transcriptional reprogramming mediates metastatic resistance to mTOR inhibition.
Academic Article First-in-Human Phase I Study of the Oral Inhibitor of Indoleamine 2,3-Dioxygenase-1 Epacadostat (INCB024360) in Patients with Advanced Solid Malignancies.
Academic Article Human melanomas and ovarian cancers overexpressing mechanical barrier molecule genes lack immune signatures and have increased patient mortality risk.
Academic Article Tumor-intrinsic oncogene pathways mediating immune avoidance.
Academic Article Phase 2 trial of talabostat in stage IV melanoma.
Academic Article Reciprocal expression of indoleamine-2,3-dioxygenase (IDO) and arginase-I in metastatic melanoma tumors.
Academic Article Immunotherapy of head and neck cancer: Emerging clinical trials from a National Cancer Institute Head and Neck Cancer Steering Committee Planning Meeting.
Academic Article Efficacy and safety of ipilimumab induction and maintenance dosing in patients with advanced melanoma who progressed on one or more prior therapies.
Academic Article Safety and efficacy of the antiganglioside GD3 antibody ecromeximab (KW2871) combined with high-dose interferon-a2b in patients with metastatic melanoma.
Academic Article The Microbiota: A New Variable Impacting Cancer Treatment Outcomes.
Academic Article Impact of oncogenic pathways on evasion of antitumour immune responses.
Academic Article The commensal microbiome is associated with anti-PD-1 efficacy in metastatic melanoma patients.
Academic Article The microbiome in cancer immunotherapy: Diagnostic tools and therapeutic strategies.
Academic Article WT1 peptide vaccine in Montanide in contrast to poly ICLC, is able to induce WT1-specific immune response with TCR clonal enrichment in myeloid leukemia.
Academic Article Oncolytic Virotherapy Promotes Intratumoral T Cell Infiltration and Improves Anti-PD-1 Immunotherapy.
Academic Article Epacadostat Plus Pembrolizumab in Patients With Advanced Solid Tumors: Phase I Results From a Multicenter, Open-Label Phase I/II Trial (ECHO-202/KEYNOTE-037).
Academic Article Safety and Clinical Activity of Pembrolizumab and Multisite Stereotactic Body Radiotherapy in Patients With Advanced Solid Tumors.
Academic Article Intratumoral CD8+ T-cell Apoptosis Is a Major Component of T-cell Dysfunction and Impedes Antitumor Immunity.
Academic Article Oncolytic Virotherapy Promotes Intratumoral T Cell Infiltration and Improves Anti-PD-1 Immunotherapy.
Academic Article High-Throughput Stability Screening of Neoantigen/HLA Complexes Improves Immunogenicity Predictions.
Academic Article Major pathologic response on biopsy (MPRbx) in patients with advanced melanoma treated with anti-PD-1: evidence for an early, on-therapy biomarker of response.
Academic Article Phase 1/2 study of epacadostat in combination with ipilimumab in patients with unresectable or metastatic melanoma.
Academic Article Epacadostat plus pembrolizumab versus placebo plus pembrolizumab in patients with unresectable or metastatic melanoma (ECHO-301/KEYNOTE-252): a phase 3, randomised, double-blind study.
Academic Article STING pathway agonism as a cancer therapeutic.
Academic Article Extended 5-Year Follow-up Results of a Phase Ib Study (BRIM7) of Vemurafenib and Cobimetinib in BRAF-Mutant Melanoma.
Academic Article ACCELERATE and European Medicines Agency Paediatric Strategy Forum for medicinal product development of checkpoint inhibitors for use in combination therapy in paediatric patients.
Academic Article Major pathologic response on biopsy (MPRbx) in patients with advanced melanoma treated with anti-PD-1: evidence for an early, on-therapy biomarker of response.
Academic Article Tumor heterogeneity and clonal cooperation influence the immune selection of IFN-?-signaling mutant cancer cells.
Academic Article Insights from immuno-oncology: the Society for Immunotherapy of Cancer Statement on access to IL-6-targeting therapies for COVID-19.
Academic Article Strategies to overcome resistance to PD-1 inhibitors.
Academic Article cDC1 dysregulation in cancer: An opportunity for intervention.
Academic Article Immunotherapy with a sting.
Academic Article Improved Survival Associated with Local Tumor Response Following Multisite Radiotherapy and Pembrolizumab: Secondary Analysis of a Phase I Trial.
Academic Article COVIDOSE: A Phase II Clinical Trial of Low-Dose Tocilizumab in the Treatment of Noncritical COVID-19 Pneumonia.
Academic Article Cancer and the Microbiome-Influence of the Commensal Microbiota on Cancer, Immune Responses, and Immunotherapy.
Academic Article Pembrolizumab Plus Ipilimumab Following Anti-PD-1/L1 Failure in Melanoma.
Academic Article Cost-Effectiveness Analysis of Adjuvant Therapy for BRAF-Mutant Resected Stage III Melanoma in Medicare Patients.
Academic Article ASO Visual Abstract: Cost-Effectiveness Analysis of Adjuvant Therapy for BRAF-Mutant Resected Stage 3 Melanoma in Medicare Patients.
Academic Article Wilms tumor reveals DNA repair gene hyperexpression is linked to lack of tumor immune infiltration.
Academic Article Randomized, Double-Blind, Placebo-Controlled, Global Phase III Trial of Talimogene Laherparepvec Combined With Pembrolizumab for Advanced Melanoma.
Academic Article Proceedings From the ASCO/College of American Pathologists Immune Checkpoint Inhibitor Predictive Biomarker Summit.
Academic Article Lymphatic coagulation and neutrophil extracellular traps in lung-draining lymph nodes of COVID-19 decedents.
Academic Article Association Between Rheumatic Autoantibodies and Immune-Related Adverse Events.
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Academic Article Tissue-resident memory T cells in immune-related adverse events: friend or foe?
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